MAP2K5 antibody (AA 63-180)

Catalog No. ABIN7539842

The Mouse Monoclonal anti-MAP2K5 antibody (Clone 5H11B10) (ABIN7539842) specifically detects MAP2K5 in WB, ELISA, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for MAP2K5 antibody (AA 63-180) (ABIN7539842)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP2K5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 5H11B10

Product Details anti-MAP2K5 Antibody

Binding Specificity: AA 63-180

Purpose: MAP2K5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Alternative Name: MAP2K5

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Molecular Weight: 50 kDa

UniProt: Q13163

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway