MAPK7 antibody (AA 411-556)

Catalog No. ABIN7539845

The Mouse Monoclonal anti-MAPK7 antibody (Clone 8H1D5) (ABIN7539845) specifically detects MAPK7 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for MAPK7 antibody (AA 411-556) (ABIN7539845)

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAPK7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 8H1D5

Product Details anti-MAPK7 Antibody

Binding Specificity: AA 411-556

Purpose: MAPK7 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MAPK7 (AA: 411-556) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MAPK7

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Alternative Name: MAPK7

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Molecular Weight: 88.4 kDa

Gene ID: 5598

UniProt: Q13164

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling