CD97 antibody (PE)

Catalog No. ABIN7540453

This anti-CD97 antibody is a Mouse Monoclonal antibody detecting CD97 in FACS. Suitable for Human.

Quick Overview for CD97 antibody (PE) (ABIN7540453)

Target: CD97

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD97 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: MEM-180

Product Details anti-CD97 Antibody (PE)

Purpose: Anti-Hu CD97 PE

Specificity: The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: PHA-activated peripheral blood cells

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CD97

Target: CD97

Alternative Name: CD97

Background:

NCBI Full Gene Name: adhesion G protein-coupled receptor E5

Description: CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.

Other names: TM7LN1, ADGRE5

Gene name: ADGRE5

Gene ID: 976

UniProt: P48960