IL-2 antibody (Biotin)

Catalog No. ABIN7540461

The Mouse Monoclonal anti-IL-2 antibody has been validated for WB, ELISA, IP, ICC and FACS. It is suitable to detect IL-2 in samples from Human.

Quick Overview for IL-2 antibody (Biotin) (ABIN7540461)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 35C3

Product Details anti-IL-2 Antibody (Biotin)

Purpose: Anti-Hu IL-2 Biotin

Specificity: The mouse monoclonal antibody 35C3 recognizes human interleukin 2 (IL-2, secreted or intracellular).

Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogen: recombinant human IL-2

Isotype: IgG2b kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 0.5-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Alternative Name: IL-2

Background:

NCBI Full Gene Name: interleukin 2

Description: IL-2 (interleukin 2) is a cytokine that is produced primarily by stimulated Th cells and its crucial role is induction of T cell proliferation. However, IL-2 also stimulates growth and differentiation of B cells, NK cells, monocytes and other cell types, such as LAK cells or oligodendrocytes and is one of the key molecules of the immune system. IL-2 signaling pathways lead to induction of Bcl-2 protein.

Other names: Interleukin 2

Gene name: IL2

Gene ID: 3558

UniProt: P60568

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation