KLRF1 antibody (Extracellular Domain) (APC)

Catalog No. ABIN7540462

The APC-conjugated Mouse Monoclonal anti-KLRF1 antibody (Clone 5D12) (ABIN7540462) specifically detects KLRF1 in FACS. The antibody is reactive with Human and Monkey samples.

Quick Overview for KLRF1 antibody (Extracellular Domain) (APC) (ABIN7540462)

Target: KLRF1 (Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLRF1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 5D12

Product Details anti-KLRF1 Antibody (APC)

Binding Specificity: Extracellular Domain

Purpose: Anti-Hu NKp80 APC

No Cross-Reactivity: Mouse, Rat

Characteristics: The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80 (CLEC5C), a C-type lectin family member, expressed on NK cells and subsets of T cells.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant human NKp80 extracellular domain

Isotype: IgG1, kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for KLRF1

Target: KLRF1 (Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1))

Alternative Name: NKp80

Background:

NCBI Full Gene Name: killer cell lectin like receptor F1

Description: NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells.

Other names: KLRF1, CLEC5C

Gene name: KLRF1

Gene ID: 51348

UniProt: Q9NZS2