SYN1 antibody (pSer62, pSer67)

Catalog No. ABIN7540655

Supplier Product No.: 612-401-e33

This Rabbit Polyclonal antibody specifically detects SYN1 in WB. It exhibits reactivity toward Rat.

Quick Overview for SYN1 antibody (pSer62, pSer67) (ABIN7540655)

Target: SYN1 (Synapsin I (SYN1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYN1 Antibody

Binding Specificity: pSer62, pSer67

Supplier Product No.: 612-401-e33

Supplier: Rockland

Purpose: Synapsin I phospho S62 + S67 Antibody

Cross-Reactivity (Details): Anti-Synapsin I pS62/67 antibody is directed against rat Synapsin I.

Purification: Synapsin I pS62/67 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Synapsin I pS62/pS67 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of Synapsin I protein.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:1000

Comment:

Suggested Applications: Titrated value sufficient to run approximately 10 mini blots.
Anti-Synapsin I pS62/pS67 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet phosphorylated at Ser62/67 in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for SYN1

Target: SYN1 (Synapsin I (SYN1))

Alternative Name: Syn1

Background: Synapsin I, SYN1, Synapsin-1,Synapsin I pS62/67 antibody detects phosphorylated Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Ser 549 along with Ser 62 and Ser 67 are the sites of Synapsin I that are phosphorylated by MAP kinase. Anti-Synapsin I pS62/pS67 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene ID: 24949

NCBI Accession: NP_001104252

UniProt: P09951