Recombinant GPC1 antibody

Catalog No. ABIN7543423

The Mouse Chimeric anti-GPC1 antibody (Clone AbAb-GPC1) (ABIN7543423) specifically detects GPC1 in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant GPC1 antibody (ABIN7543423)

Target: GPC1 (Glypican 1 (GPC1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Chimeric

Conjugate: This GPC1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: AbAb-GPC1

Product Details anti-GPC1 Antibody

Purpose: Anti-Glypican-1 [AbAb-GPC1], Mouse IgG1, kappa

Specificity:

This antibody binds human glypican-1, which is a cell surface proteoglycan that bears heparan sulfate. This protein is required for skeletal muscle differentiation. Glypican-1 (GPC1) was significantly expressed in serum exosomes of patients with pancreatic cancer and so GPC1 is considered as a tumor marker for pancreatic cancer.

Application Notes original Clone: The binding characterization of this antibody to human glypican-1 was determined using ELISA. The binding of this antibody to human glypican-1 expressed on the surface of human breast cancer cell line MDA-MB-231 was determined using flow cytometry (CN112300283).

Characteristics: This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing 6-week-old healthy New Zealand female white rabbits subcutaneously with human glypican-1.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Rabbit

OriginalFormat: IgG

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for GPC1

Target: GPC1 (Glypican 1 (GPC1))

Alternative Name: Glypican-1

Background: GPC1

UniProt: P35052

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation