Presenilin 1 antibody (pSer353)

Catalog No. ABIN7543989

This Rabbit Polyclonal antibody specifically detects Presenilin 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Presenilin 1 antibody (pSer353) (ABIN7543989)

Target: Presenilin 1 (PSEN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Presenilin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Presenilin 1 Antibody

Binding Specificity: pSer353

Expression System: HEK-293 Cells

Purpose: Rabbit polyclonal antibody to Presenilin 1 (Phospho-S353)

Specificity: Recognizes endogenous levels of Presenilin 1 protein only when phosphorylated at S353

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S353 of human Presenilin 1. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for Presenilin 1

Target: Presenilin 1 (PSEN1)

Alternative Name: PSEN1

Background: Alternative Names: AD3, PS1, PSNL1, Presenilin-1, PS-1, Protein S182

Gene ID: 5663

UniProt: P49768

Pathways: Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport