CD226 antibody (PE)

Catalog No. ABIN7566565

This Mouse Monoclonal antibody specifically detects CD226 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD226 antibody (PE) (ABIN7566565)

Target: CD226

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD226 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 11A8

Product Details anti-CD226 Antibody (PE)

Purpose: PE Anti-Human CD226/DNAM-1 Antibody[11A8]

Isotype: IgG1, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Comment:

Matching Isotype Control: (ABIN7469761)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: CD226,DNAM-1

Background: DNAM-1,PTA1,TLiSA1,DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligands for CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), which are broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physically associated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediated signaling.

Gene ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints