FAS antibody (PE,Cy7)

Catalog No. ABIN7566609

The PE,Cy7-conjugated Mouse Monoclonal anti-FAS antibody (Clone HFE7A-APO) (ABIN7566609) specifically detects FAS in FACS. The antibody is reactive with Human samples.

Quick Overview for FAS antibody (PE,Cy7) (ABIN7566609)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAS antibody is conjugated to PE,Cy7

Application: Flow Cytometry (FACS)

Clone: HFE7A-APO

Product Details anti-FAS Antibody (PE,Cy7)

Purpose: PE/Cyanine7 Anti-Human CD95/Fas Antibody[HFE7A/APO]

Isotype: IgG2a, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Comment:

Matching Isotype Control: (ABIN7469781)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: CD95/Fas

Background: APT1,FAS1,TNFRSF6,Apo-1 antigen,FASLG receptor,CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.

Gene ID: 355

UniProt: P25445

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity