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DLG4 antibody (AA 468-560) (FITC)

This anti-DLG4 antibody is a Rabbit Polyclonal antibody detecting DLG4 in WB, FACS, IF (cc) and IF (p). Suitable for Rat, Human, Mouse and Monkey.
Catalog No. ABIN725937

Quick Overview for DLG4 antibody (AA 468-560) (FITC) (ABIN725937)

Target

See all DLG4 Antibodies
DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Reactivity

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  • 119
  • 29
  • 17
  • 4
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Rat, Human, Mouse, Monkey

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 2
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  • 1
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This DLG4 antibody is conjugated to FITC

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    AA 468-560

    Cross-Reactivity

    Human, Monkey, Mouse, Rat

    Predicted Reactivity

    Dog,Cow,Pig,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PSD95

    Isotype

    IgG
  • Application Notes

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

    Alternative Name

    PSD95

    Background

    Synonyms: PSD95, SAP9, SAP-9, Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 9, DLG4

    Background: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

    Gene ID

    1742

    UniProt

    P78352

    Pathways

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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