NMNAT1 antibody (AA 19-609)

Catalog No. ABIN7596021

This Mouse Monoclonal antibody specifically detects NMNAT1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for NMNAT1 antibody (AA 19-609) (ABIN7596021)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NMNAT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: AT4G8

Product Details anti-NMNAT1 Antibody

Binding Specificity: AA 19-609

Purpose: Human NMNAT-1 antibody

Purification: Purified

Immunogen: Recombinant human NMNAT1 (19-609aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Alternative Name: NMNAT-1

Background: NMNAT1, also known as NMNAT or PNAT1, is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD. It is widely expressed with high levels in skeletal muscle, heart, liver and kidney. This protein appears to have the ability to protect against axonal degeneration following mechanical or toxic insults.

NCBI Accession: NP_073624