KAT2A antibody (AA 411-837)
Quick Overview for KAT2A antibody (AA 411-837) (ABIN7596032)
Target
See all KAT2A AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 411-837
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Purpose
- Human KAT2A/GCN5 antibody
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Purification
- Purified
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Immunogen
- Recombinant human GCN5L2 (411-837aa) purified from E. coli
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Isotype
- IgG2a kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
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Alternative Name
- KAT2A/GCN5
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Background
- GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation toprovide the additional components important for acetylation. GCN5L2 can be one of the potential enzymesinvolved in acetylation in vivo. GCN5L2 is expressed predominantly in the embryo and newborn and is essentialfor normal embryonic development. Therefore, GCN5L2 appears to be important for differentiation ofembryonic-derived preadipocytes. On the one hand, loss of GCN5L2 leads to high incidence of apoptosis inthe GCN5L2 mutants that begins before the onset of morphological abnormality.
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NCBI Accession
- NP_066564
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Pathways
- Chromatin Binding, Tube Formation
Target
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