IL-15 antibody (AA 49-162)

Catalog No. ABIN7596105

This Mouse Monoclonal antibody specifically detects IL-15 in WB, ICC, ELISA, FACS and IF. It exhibits reactivity toward Human.

Quick Overview for IL-15 antibody (AA 49-162) (ABIN7596105)

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-15 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: AT7G9

Product Details anti-IL-15 Antibody

Binding Specificity: AA 49-162

Purpose: Human IL-15 antibody

Purification: Purified

Immunogen: Recombinant human IL-15 (49-162aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for IL-15

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Alternative Name: IL-15

Background: Interleukin-15 (IL-15) is a pleiotropic cytokine that plays a crucial role in both innate and adaptive immunity. IL-15 is unique among cytokines due to its involvement in a trans-signaling mechanism. In this process, IL-15 receptor alpha (IL-15Rα) from one subset of cells presents IL-15 to neighboring cells that express IL-2Rβ/γc. This cytokine is produced by a wide variety of cells and tissues. Similar to IL-2, IL-15 stimulates the proliferation of T-lymphocytes and induces the generation of cytotoxic T-lymphocytes (CTLs) and lymphokine-activated killer (LAK) cells.

NCBI Accession: NP_000576

Pathways: JAK-STAT Signaling, Glycosaminoglycan Metabolic Process