FGF2 antibody (AA 143-250)

Catalog No. ABIN726425

The Rabbit Polyclonal anti-FGF2 antibody has been validated for WB, ELISA, FACS, IHC (p), IF (cc), IF (p) and IHC (fro). It is suitable to detect FGF2 in samples from Human, Mouse, Rat, Rabbit and Sheep. There are 18+ publications available.

Quick Overview for FGF2 antibody (AA 143-250) (ABIN726425)

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Reactivity: Human, Mouse, Rat, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FGF2 Antibody

Binding Specificity: AA 143-250

Cross-Reactivity: Human, Mouse, Rabbit, Rat, Sheep

Predicted Reactivity: Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse FGF2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-FGF2 antibody (ABIN726425)

Zhang, Jiang, Chen, Hu, Yang, Liu et al.: "Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with ..." in: Journal of cellular physiology, Vol. 234, Issue 10, pp. 18544-18559, (2020) (PubMed).

Liu, Lu, Chen, Zhang, Wang, Li, Zhang: "B-cell leukemia/lymphoma 10 promotes angiogenesis in an experimental corneal neovascularization model." in: Eye (London, England), Vol. 32, Issue 7, pp. 1220-1231, (2019) (PubMed).

Peng, Zhang, Zhang, Zhao, Dong: "Expression of osteoprotegerin and receptor activator for the nuclear factor-κB ligand in XACB/LV-bFGF/MSCs transplantation for repair of rabbit femoral head defect necrosis." in: Journal of cellular biochemistry, (2018) (PubMed).

Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

Shkurupy, Arkhipov, Neshchadim, Akhramenko, Troitskii: "In vitro effects of nanosized diamond particles on macrophages." in: Bulletin of experimental biology and medicine, Vol. 158, Issue 4, pp. 500-3, (2015) (PubMed).

He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." in: Cancer letters, Vol. 368, Issue 1, pp. 115-25, (2015) (PubMed).

Lee, Lee, Kim, Yang: "Anti-neovascular effect of chondrocyte-derived extracellular matrix on corneal alkaline burns in rabbits." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 252, Issue 6, pp. 951-61, (2014) (PubMed).

Turgut, Eren, Akin, Bilir Can, Demir: "Impact of trastuzumab on wound healing in experimental glaucoma surgery." in: Clinical & experimental ophthalmology, (2014) (PubMed).

Turgut, Eren, Ak?n, Demir, Kobat: "Topical infliximab for the suppression of wound healing following experimental glaucoma filtration surgery." in: Drug design, development and therapy, Vol. 8, pp. 421-9, (2014) (PubMed).

Sun, Pan, Shi, Zhang, Zhang, Ye, Liu, Zhang, Zhong, Yuan: "Structural integrity, immunogenicity and biomechanical evaluation of rabbit decelluarized tracheal matrix." in: Journal of biomedical materials research. Part A, (2014) (PubMed).

Wang, Gao, Xiong, Hu, Liu, He: "VEGF and BFGF Expression and Histological Characteristics of the Bone-Tendon Junction during Acute Injury Healing." in: Journal of sports science & medicine, Vol. 13, Issue 1, pp. 15-21, (2014) (PubMed).

Chen, Wang, Chen, Ma: "Altered TGF-?2 and bFGF expression in scleral desmocytes from an experimentally-induced myopia guinea pig model." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 251, Issue 4, pp. 1133-44, (2013) (PubMed).

Pan, Wang, Xiang, Shao: "Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantation." in: The Journal of biological chemistry, Vol. 286, Issue 14, pp. 12340-8, (2011) (PubMed).

Zhao, Cao, Liu, Xiao, Tang, Wang, Liang: "Effects of recombinant human endostatin on peritoneal angiogenesis in peritoneal dialysis rats." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 6, pp. 599-606, (2011) (PubMed).

Gao, Zhao, Liang, Li, Cao, Liu: "Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 8, pp. 736-42, (2011) (PubMed).

Liu, Xu, Yang, Chen, Liu, Li, Li: "Analysis of olfactory ensheathing glia transplantation-induced repair of spinal cord injury by electrophysiological, behavioral, and histochemical methods in rats." in: Journal of molecular neuroscience : MN, Vol. 41, Issue 1, pp. 25-9, (2010) (PubMed).

Target Details for FGF2

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Alternative Name: bFGF

Background:

Synonyms: Fgfb, bFGF, Fgf-2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2, HBGF-2, Fgf2

Background: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity).

Gene ID: 14173

UniProt: P09038

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins