FYCO1 antibody (AA 1-1019)
Quick Overview for FYCO1 antibody (AA 1-1019) (ABIN7598934)
Target
See all FYCO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 1-1019
-
Purpose
- Anti-FYCO1 Antibody
-
Cross-Reactivity (Details)
- No cross-reactivity with other proteins
-
Characteristics
- Anti-FYCO1 Antibody (ABIN7598934). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human FYCO1 recombinant protein (Position: M1-K1019). Human FYCO1 shares 72.2% amino acid (aa) sequence identity with mouse FYCO1.
-
Isotype
- IgG
-
-
-
-
Application Notes
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))
-
Alternative Name
- FYCO1
-
Background
-
Synonyms: FYCO1, ZFYVE7, FYVE and coiled-coil domain-containing protein 1, Zinc finger FYVE domain-containing protein 7
Background: The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2).
-
Molecular Weight
- 167 kDa
-
Gene ID
- 79443
-
Pathways
- SARS-CoV-2 Protein Interactome
Target
-