PHPT1 antibody (AA 1-125)

Catalog No. ABIN7598972

The Rabbit Polyclonal anti-PHPT1 antibody (ABIN7598972) specifically detects PHPT1 in WB, IHC, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PHPT1 antibody (AA 1-125) (ABIN7598972)

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHPT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-PHPT1 Antibody

Binding Specificity: AA 1-125

Purpose: Anti-PHPT1 Antibody

Predicted Reactivity: Human PHPT1 shares 84.4% amino acid (aa) sequence identity with mouse PHPT1.

Characteristics: Anti-PHPT1 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHPT1 recombinant protein (Position: M1-Y125). Human PHPT1 shares 84.4% amino acid (aa) sequence identity with mouse PHPT1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PHPT1

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Alternative Name: PHPT1

Background:

Background: 14 kDa phosphohistidine phosphatase is an enzyme that in humans is encoded by the PHPT1 gene. This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphohistidine phosphatase 1

Molecular Weight: 14 kDa

Gene ID: 29085

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion