TOR1AIP1 antibody (AA 1-445)

Catalog No. ABIN7599399

This anti-TOR1AIP1 antibody is a Rabbit Polyclonal antibody detecting TOR1AIP1 in WB, ELISA, IF and ICC. Suitable for Human.

Quick Overview for TOR1AIP1 antibody (AA 1-445) (ABIN7599399)

Target: TOR1AIP1 (Torsin A Interacting Protein 1 (TOR1AIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR1AIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-TOR1AIP1 Antibody

Binding Specificity: AA 1-445

Purpose: Anti-TOR1AIP1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TOR1AIP1 Antibody Picoband® (ABIN7599399). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TOR1AIP1 recombinant protein (Position: M1-D445).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dorboz, I., Coutelier, M., Bertrand, A. T., Caberg, J.-H., Elmaleh-Berges, M., Laine, J., Stevanin, G., Bonne, G., Boespflug-Tanguy, O., Servais, L. Severe dystonia, cerebellar atrophy, and cardiomyopathy likely caused by a missense mutation in TOR1AIP1. Orphanet J. Rare Dis. 9: 174, 2014. Note: Electronic Article. 2. Goodchild, R. E., Dauer, W. T. The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein. J. Cell Biol. 168: 855-862, 2005. 3. Kayman-Kurekci, G., Korkusuz, P., Dincer, P. Response (to Sewry and Gobel). (Letter) Neuromusc. Disord. 24: 1122 only, 2014.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TOR1AIP1

Target: TOR1AIP1 (Torsin A Interacting Protein 1 (TOR1AIP1))

Alternative Name: TOR1AIP1

Background:

Synonyms: Pancreatic secretory granule membrane major glycoprotein GP2, Pancreatic zymogen granule membrane protein GP-2, Gp2

Tissue Specificity: Expressed in all tissues tested including, liver, heart, adipose tissue, mammary gland, testes, ovary, brain, kidney and muscle. Highest levels in liver.

Background: Torsin-1A-interacting protein 1 is a protein that in humans is encoded by the TOR1AIP1 gene. This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants.

Molecular Weight: 66 kDa

Gene ID: 26092

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection