GSDMD antibody (AA 1-484)

Catalog No. ABIN7599433

This Mouse Monoclonal antibody specifically detects GSDMD in WB, IF, IHC, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for GSDMD antibody (AA 1-484) (ABIN7599433)

Target: GSDMD (Gasdermin D (GSDMD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSDMD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 6D11

Product Details anti-GSDMD Antibody

Binding Specificity: AA 1-484

Purpose: Anti-GSDMD Antibody (monoclonal, 6D11)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-GSDMD Antibody.(monoclonal, 6D11). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GSDMD recombinant protein (Position: M1-H484).

Isotype: IgG2b

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Alternative Name: GSDMD

Background:

Background: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Gene Full Name: gasdermin D

Molecular Weight: 53 kDa

Gene ID: 79792

UniProt: P57764

Pathways: Inflammasome