UBR2 antibody (AA 10-664)

Catalog No. ABIN7599610

This Mouse Monoclonal antibody specifically detects UBR2 in WB. It exhibits reactivity toward Human.

Quick Overview for UBR2 antibody (AA 10-664) (ABIN7599610)

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBR2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 2G10

Product Details anti-UBR2 Antibody

Binding Specificity: AA 10-664

Purpose: Anti-UBR2 Antibody (monoclonal, 2G10)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-UBR2 Antibody (monoclonal, 2G10) (ABIN7599610). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UBR2 recombinant protein (Position: Q10-A664).

Isotype: IgG2a

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for UBR2

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Alternative Name: UBR2

Background:

Synonyms: Tubulin beta chain, Tubulin beta-5 chain, TUBB, TUBB5, OK/SW-cl.56

Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.

Background: E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 202 kDa

Gene ID: 23304