MEF2B antibody (AA 127-352)
Quick Overview for MEF2B antibody (AA 127-352) (ABIN7599892)
Target
See all MEF2B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 127-352
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Purpose
- Anti-MEF2B Antibody Picoband®
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-MEF2B Antibody Picoband® (ABIN7599892). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human MEF2B recombinant protein (Position: R127-D352).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Han, A., Pan, F., Stroud, J. C., Youn, H.-D., Liu, J. O., Chen, L. Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2. Nature 422: 730-734, 2003. 2. Hobson, G. M., Krahe, R., Garcia, E., Siciliano, M. J., Funanage, V. L. Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23. Genomics 29: 704-711, 1995. 3. Morin, R. D., Mendez-Lago, M., Mungall, A. J., Goya, R., Mungall, K. L., Corbett, R. D., Johnson, N. A., Severson, T. M., Chiu, R., Field, M., Jackman, S., Krzywinski, M., and 38 others. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 476: 298-303, 2011. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
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Alternative Name
- MEF2B
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Background
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Synonyms: Activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, p38, AHSA1, C14orf3, HSPC322
Tissue Specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Background: Myocyte enhancer binding factor 2B (MEF2B) is a transcription factor part of the MEF2 gene family including MEF2A, MEF2C, and MEF2D. The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207.
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Molecular Weight
- 50 kDa
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Gene ID
- 100271849
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UniProt
- Q02080
Target
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