WDR77 antibody (AA 13-295)

Catalog No. ABIN7599934

This anti-WDR77 antibody is a Rabbit Polyclonal antibody detecting WDR77 in WB and ELISA. Suitable for Human.

Quick Overview for WDR77 antibody (AA 13-295) (ABIN7599934)

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR77 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-WDR77 Antibody

Binding Specificity: AA 13-295

Purpose: Anti-WDR77 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-WDR77 Antibody Picoband® (ABIN7599934). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WDR77 recombinant protein (Position: A13-A295).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Friesen, W. J., Wyce, A., Paushkin, S., Abel, L., Rappsilbers, J., Mann, M., Dreyfuss, G. A novel WD repeat protein component of the methylosome binds Sm proteins. J. Biol. Chem. 277: 8243-8247, 2002. 2. Furuno, K., Masatsugu, T., Sonoda, M., Sasazuki, T., Yamamoto, K. Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro. Biochem. Biophys. Res. Commun. 345: 1051-1058, 2006. 3. Gross, M. B. Personal Communication. Baltimore, Md. 3/2/2018.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Alternative Name: WDR77

Background:

Synonyms: Vesicular acetylcholine transporter,VAChT,Solute carrier family 18 member 3,SLC18A3,VACHT,

Tissue Specificity: Peripheral and central cholinergic nervous systems. .

Background: Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene. The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 42 kDa

Gene ID: 79084

Pathways: Ribonucleoprotein Complex Subunit Organization