RAB43 antibody (AA 14-206)

Catalog No. ABIN7600010

Product Details anti-RAB43 Antibody

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Binding Specificity: AA 14-206

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB43 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Purpose: Anti-RAB43 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RAB43 Antibody Picoband® (ABIN7600010). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RAB43 recombinant protein (Position: Q14-E206).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jiang, Y. , Sun, Y. , Hu, J. , Yu, N. , & Xu, H. . (2019). A germline mutation in rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome. BMC Cancer, 19(1). 2. ChunmanLi, ZheWei, YiFan, WeiHuang, YunchaoSu, & HonglinLi, et al. (2017). The gtpase rab43 controls the anterograde er-golgi trafficking and sorting of gpcrs. Cell Reports. 3. Ming-Zhi, Han, Bin, Huang, An-Jing, & Chen, et al. (2017). High expression of rab43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas. Oncology reports.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RAB43

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Alternative Name: RAB43 (RAB43 Products)

Background:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: Ras-related GTP-binding protein 43 (RAB43) is a member ofthe Rassuperfamily. RAB43 is mainly located in endoplasmic reticulum and Golgi, and plays a role as a key regulator of vesicle movement,signal transduction and tethering membrane eventsin membrane trafficking.

Molecular Weight: 23 kDa

Gene ID: 339122