Espin antibody (AA 143-854)
Quick Overview for Espin antibody (AA 143-854) (ABIN7600060)
Target
See all Espin (ESPN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 143-854
-
Purpose
- Anti-ESPN Antibody
-
Cross-Reactivity (Details)
- No cross-reactivity with other proteins
-
Predicted Reactivity
- Human ESPN shares 75.6%,78.1% amino acid (aa) sequence identity with mouse,rat ESPN,respectively.
-
Characteristics
- Anti-ESPN Antibody. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human ESPN recombinant protein (Position: H143-Y854). Human ESPN shares 75.6% and 78.1% amino acid (aa) sequence identity with mouse and rat ESPN, respectively.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
-
-
- Espin (ESPN)
-
Alternative Name
- ESPN
-
Background
-
Background: This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
Gene Full Name: espin
-
Molecular Weight
- 110 kDa
-
Gene ID
- 83715
-
UniProt
- B1AK53
-
Pathways
- Sensory Perception of Sound
Target
-