IL-34 antibody (AA 21-48)

Catalog No. ABIN7600622

This anti-IL-34 antibody is a Rabbit Polyclonal antibody detecting IL-34 in WB, ELISA and IHC. Suitable for Human.

Quick Overview for IL-34 antibody (AA 21-48) (ABIN7600622)

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-34 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IL-34 Antibody

Binding Specificity: AA 21-48

Purpose: Anti-IL34 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IL34 Antibody Picoband® (ABIN7600622). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IL34 recombinant protein (Position: N21-R48).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 5/30/2014. 2. Lin, H., Lee, E., Hestir, K., Leo, C., Huang, M., Bosch, E., Halenbeck, R., Wu, G., Zhou, A., Behrens, D., Hollenbaugh, D., Linnemann, T., Qin, M., Wong, J., Chu, K., Doberstein, S. K., Williams, L. T. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science 320: 807-811, 2008.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for IL-34

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Alternative Name: IL34

Background:

Synonyms: Interleukin-34, IL-34, IL34, C16orf77

Tissue Specificity: Detected in the sinusoidal epithelium in the red pulp of spleen. Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

Background: Interleukin 34 (IL-34) is a protein belonging to a group of cytokines called interleukins. It was originally identified in humans, by large scale screening of secreted proteins, chimpanzee, murine, rat and chicken interleukin 34 orthologs have also been found. The protein is composed of 241 amino acids, 39 kilodaltons in mass, and forms homodimers. IL-34 increases growth or survival of immune cells known as monocytes, it elicits its activity by binding the Colony stimulating factor 1 receptor. This gene is mapped to 16q22.1.

Molecular Weight: 45 kDa

Gene ID: 146433

Pathways: RTK Signaling