SCD antibody (AA 26-358)

Catalog No. ABIN7600957

The Rabbit Polyclonal anti-SCD antibody has been validated for WB, ELISA, ICC, IF, IP and FACS. It is suitable to detect SCD in samples from Human.

Quick Overview for SCD antibody (AA 26-358) (ABIN7600957)

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-SCD Antibody

Binding Specificity: AA 26-358

Purpose: Anti-SCD Antibody Picoband®

Characteristics: Anti-SCD Antibody Picoband® (ABIN7600957). Tested in WB, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCD recombinant protein (Position: R26-S358).

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bai, Y., McCoy, J. G., Levin, E. J., Sobrado, P., Rajashankar, K. R., Fox, B. G., Zhou, M. X-ray structure of a mammalian stearoyl-CoA desaturase. Nature 524: 252-256, 2015. 2. Bogie, J. F. J., Grajchen, E., Wouters, E., Corrales, A. G., Dierckx, T., Vanherle, S., Mailleux, J., Gervois, P., Wolfs, E., Dehairs, J., Van Broeckhoven, J., Bowman, A. P., and 10 others. Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain. J. Exp. Med. 217: e20191660, 2020. 3. Chu, K., Miyazaki, M., Man, W. C., Ntambi, J. M. Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation. Molec. Cell. Biol. 26: 6786-6798, 2006.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SCD

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Alternative Name: SCD

Background: This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17.

Molecular Weight: 37 kDa

Gene ID: 6319

UniProt: O00767

Pathways: Brown Fat Cell Differentiation