SYNE2 antibody (AA 3765-5590)

Catalog No. ABIN7601532

This Rabbit Polyclonal antibody specifically detects SYNE2 in WB, ELISA, IHC, IF, ICC and FACS. It exhibits reactivity toward Human and Monkey.

Quick Overview for SYNE2 antibody (AA 3765-5590) (ABIN7601532)

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-SYNE2 Antibody

Binding Specificity: AA 3765-5590

Purpose: Anti-Nesprin 2/SYNE2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Nesprin 2/SYNE2 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Nesprin 2/SYNE2 recombinant protein (Position: Q3765-Q5590).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Monkey Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SYNE2

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Alternative Name: SYNE2

Background:

Background: Nesprin-2 is a protein that in humans is encoded by the SYNE2 gene. The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: spectrin repeat containing nuclear envelope protein 2

Molecular Weight: 50-60 kDa

Gene ID: 23224

UniProt: Q8WXH0

Pathways: Maintenance of Protein Location