Leupaxin antibody (AA 45-323)

Catalog No. ABIN7601770

The Rabbit Polyclonal anti-Leupaxin antibody is suitable to detect Leupaxin in samples from Human and Mouse. It has been validated for WB, ELISA, FACS, ICC and IF.

Quick Overview for Leupaxin antibody (AA 45-323) (ABIN7601770)

Target: Leupaxin (LPXN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Leupaxin Antibody

Binding Specificity: AA 45-323

Purpose: Anti-LPXN Antibody

Predicted Reactivity: Human LPXN shares 89.5% amino acid (aa) sequence identity with mouse LPXN.

Characteristics: Anti-LPXN Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LPXN recombinant protein (Position: E45-H323). Human LPXN shares 89.5% amino acid (aa) sequence identity with mouse LPXN.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: LPXN

Background:

Background: Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity.

Gene Full Name: leupaxin

Molecular Weight: 43 kDa

Gene ID: 9404

UniProt: O60711