PLVAP antibody (AA 51-422)

Catalog No. ABIN7601934

This Rabbit Polyclonal antibody specifically detects PLVAP in WB, FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for PLVAP antibody (AA 51-422) (ABIN7601934)

Target: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLVAP antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-PLVAP Antibody

Binding Specificity: AA 51-422

Purpose: Anti-PLVAP Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PLVAP Antibody Picoband® (ABIN7601934). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLVAP recombinant protein (Position: N51-K422).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Broekaert, I. J., Becker, K., Gottschalk, I., Korber F., Dotsch, J., Thiele, H., Altmuller, J., Nurnberg, P., Hunseler, C., Cirak, S. Mutations in plasmalemma vesicle-associated protein cause severe syndromic protein-losing enteropathy.. J. Med. Genet. 55: 637-640, 2018. 2. Elkadri, A., Thoeni, C., Deharvengt, S. J., Murchie, R., Guo, C., Stavropoulos, J. D., Marshall, C. R., Wales, P., Bandsma, R. H. J., Cutz, E., Roifman, C. M., Chitayat, D., Avitzur, Y., Stan, R. V., Muise A. M. Mutations in plasmalemma vesicle associated protein result in sieving protein-losing enteropathy characterized by hypoproteinemia, hypoalbuminemia, and hypertriglyceridemia. Cell. Molec. Gastroent. Hepatol. 1: 381-394, 2015. 3. Herrnberger, L., Seitz, R., Kuespert, S., Bosl, M. R., Fuchshofer, R., Tamm, E. R. Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem. Cell Biol. 138: 709-724, 2012.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for PLVAP

Target: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Alternative Name: PLVAP

Background:

Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1

Tissue Specificity: Expressed in kidney.

Background: Plasmalemma vesicle-associated protein is a protein that in humans is encoded by the PLVAP gene. Predicted to enable identical protein binding activity. Involved in MAPK cascade, positive regulation of cellular extravasation, and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Colocalizes with caveola. Implicated in congenital diarrhea.

Molecular Weight: 53 kDa

Gene ID: 83483