FAP antibody (AA 65-580)

Catalog No. ABIN7602234

This Rabbit Polyclonal antibody specifically detects FAP in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for FAP antibody (AA 65-580) (ABIN7602234)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-FAP Antibody

Binding Specificity: AA 65-580

Purpose: Anti-Fibroblast activation protein, alpha/FAP Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Fibroblast activation protein, alpha/FAP Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibroblast activation protein, alpha/FAP recombinant protein (Position: Q65-Q580).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: FAP

Background:

Background: Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that in humans is encoded by the FAP gene. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: fibroblast activation protein alpha

Molecular Weight: 97 kDa

Gene ID: 2191

UniProt: Q12884

Pathways: Tube Formation