PMPCA antibody (AA 99-525)

Catalog No. ABIN7602722

The Rabbit Polyclonal anti-PMPCA antibody (ABIN7602722) specifically detects PMPCA in WB, ELISA, FACS, IHC, ICC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PMPCA antibody (AA 99-525) (ABIN7602722)

Target: PMPCA (Peptidase (Mitochondrial Processing) alpha (PMPCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMPCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-PMPCA Antibody

Binding Specificity: AA 99-525

Purpose: Anti-PMPCA/INPP5 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PMPCA/INPP5 Antibody (ABIN7602722). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PMPCA/INPP5 recombinant protein (Position: R99-R525).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for PMPCA

Target: PMPCA (Peptidase (Mitochondrial Processing) alpha (PMPCA))

Alternative Name: PMPCA

Background:

Synonyms: Peflin, PEF protein with a long N-terminal hydrophobic domain, Penta-EF hand domain-containing protein 1, PEF1, ABP32, UNQ1845, PRO3573

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: Mitochondrial-processing peptidase subunit alpha is an enzyme that in humans is encoded by the PMPCA gene. The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.

Molecular Weight: 50-58 kDa

Gene ID: 23203

UniProt: Q10713

Pathways: Inositol Metabolic Process, SARS-CoV-2 Protein Interactome