BTK antibody (pTyr223)

Catalog No. ABIN7603446

This Rabbit Monoclonal antibody specifically detects BTK in WB and IP. It exhibits reactivity toward Human.

Quick Overview for BTK antibody (pTyr223) (ABIN7603446)

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BTK antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: ECD-2

Product Details anti-BTK Antibody

Binding Specificity: pTyr223

Purpose: Anti-Phospho-BTK (Y223) Rabbit Monoclonal Antibody

Characteristics: Anti-Phospho-BTK Rabbit Monoclonal Antibody (ABIN7603446). Tested in WB, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-BTK (Y223)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IP 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for BTK

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Alternative Name: BTK

Background:

Synonyms: Tyrosine-protein kinase BTK,2.7.10.2,Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase,BTK,AGMX1, ATK, BPK,

Tissue Specificity: Predominantly expressed in B-lymphocytes.

Molecular Weight: 100-110 kDa

UniProt: Q06187

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling