APEX1 antibody

Catalog No. ABIN7604007

This Rabbit Monoclonal antibody specifically detects APEX1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for APEX1 antibody (ABIN7604007)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This APEX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 17A44

Product Details anti-APEX1 Antibody

Purpose: Anti-APE1 Rabbit Monoclonal Antibody

Characteristics: Anti-APE1 Rabbit Monoclonal Antibody (ABIN7604007). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human APE1

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: APEX1

Background:

Synonyms: Nuclear receptor subfamily 4 group A member 1,Early response protein NAK1,Nuclear hormone receptor NUR/77,Nur77,Orphan nuclear receptor HMR,Orphan nuclear receptor TR3,ST-59,Testicular receptor 3,NR4A1,GFRP1, HMR, NAK1,

Tissue Specificity: Fetal muscle and adult liver, brain and thyroid.

Molecular Weight: 36 kDa

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus