BIM antibody

Catalog No. ABIN7604132

This anti-BIM antibody is a Rabbit Monoclonal antibody detecting BIM in WB, IHC, IF, ICC, FACS and IP. Suitable for Human, Mouse and Rat.

Quick Overview for BIM antibody (ABIN7604132)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: CBE-2

Product Details anti-BIM Antibody

Purpose: Anti-Bim BCL2L11 Rabbit Monoclonal Antibody

Characteristics: Anti-Bim BCL2L11 Rabbit Monoclonal Antibody (ABIN7604132). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Bim

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000
IHC 1:50-1:100
ICC/IF 1:50-1:100
IP 1:40
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: BCL2L11

Background:

Synonyms: Bcl-2-like protein 11,Bcl2-L-11,Bcl2-interacting mediator of cell death,BCL2L11,BIM,

Tissue Specificity: Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. .

Molecular Weight: 65-80 kDa

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity