Caspase 1 antibody

Catalog No. ABIN7604224

The Rabbit Monoclonal anti-Caspase 1 antibody has been validated for WB and IP. It is suitable to detect Caspase 1 in samples from Human, Mouse and Rat.

Quick Overview for Caspase 1 antibody (ABIN7604224)

Target: Caspase 1 (CASP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 26C50

Product Details anti-Caspase 1 Antibody

Purpose: Anti-Caspase-1 + p10 + p12 Rabbit Monoclonal Antibody

Characteristics: Anti-Caspase-1 + p10 + p12 Rabbit Monoclonal Antibody (ABIN7604224). Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from Caspase-1 + p10 + p12

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1

Background:

Synonyms: Caspase-1,CASP-1,3.4.22.36,Interleukin-1 beta convertase,IL-1BC,Interleukin-1 beta-converting enzyme,ICE,IL-1 beta-converting enzyme,p45,Caspase-1 subunit p20,Caspase-1 subunit p10,CASP1,IL1BC, IL1BCE,

Tissue Specificity: Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain. .

Molecular Weight: 45 kDa, 42 kDa, 35 kDa, 12 kDa, 10 kDa

UniProt: P29466

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome