CENPE antibody

Catalog No. ABIN7604418

This Rabbit Monoclonal antibody specifically detects CENPE in WB. It exhibits reactivity toward Human.

Quick Overview for CENPE antibody (ABIN7604418)

Target: CENPE (Centromere Protein E, 312kDa (CENPE))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CENPE antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ACDI-3

Product Details anti-CENPE Antibody

Purpose: Anti-CENPE Monoclonal Antibody

Characteristics: Anti-CENPE Monoclonal Antibody (ABIN7604418). Tested in WB application. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CENPE

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CENPE

Target: CENPE (Centromere Protein E, 312kDa (CENPE))

Alternative Name: CENPE

Background:

Synonyms: G1/S-specific cyclin-E2,CCNE2,

Tissue Specificity: According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.

Molecular Weight: 17 kDa

UniProt: Q02224

Pathways: M Phase, Maintenance of Protein Location