ERBB4 antibody

Catalog No. ABIN7604769

This Rabbit Monoclonal antibody specifically detects ERBB4 in WB, IF, FACS, ICC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ERBB4 antibody (ABIN7604769)

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ERBB4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: HC-5

Product Details anti-ERBB4 Antibody

Purpose: Anti-ErbB (HER4) ERBB4 Rabbit Monoclonal Antibody

Characteristics: Anti-ErbB (HER4) ERBB4 Rabbit Monoclonal Antibody (ABIN7604769). Tested in WB, ICC/IF, Flow Cytometry, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human ErbB (HER4)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ICC/IF 1:50-1:200
FC 1:40
IP 1:30

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for ERBB4

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Alternative Name: ERBB4

Background:

Synonyms: Receptor tyrosine-protein kinase erbB-4,2.7.10.1,Proto-oncogene-like protein c-ErbB-4,Tyrosine kinase-type cell surface receptor HER4,p180erbB4,ERBB4 intracellular domain,4ICD,E4ICD,s80HER4,ERBB4,HER4,

Tissue Specificity: Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A CYT-1 and isoform JM-B CYT-1 are expressed in cerebellum, but only the isoform JM-B is expressed in the heart. .

Molecular Weight: 3 kDa

UniProt: Q15303

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway