Geminin antibody

Catalog No. ABIN7604960

The Rabbit Monoclonal anti-Geminin antibody (Clone AEGO-7) (ABIN7604960) specifically detects Geminin in WB, IHC, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for Geminin antibody (ABIN7604960)

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Geminin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AEGO-7

Product Details anti-Geminin Antibody

Purpose: Anti-Geminin Monoclonal Antibody

Characteristics: Anti-Geminin Monoclonal Antibody. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Geminin Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000IHC 1:50-200ICC/IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Geminin

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Alternative Name: GMNN

Background: Geminin DNA replication inhibitor

Molecular Weight: 63 kDa

Gene ID: 51053

UniProt: O75496

Pathways: EGFR Signaling Pathway, DNA Replication