HIP1 antibody

Catalog No. ABIN7605099

This Rabbit Monoclonal antibody specifically detects HIP1 in WB, IP, IF and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HIP1 antibody (ABIN7605099)

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AFG-8

Product Details anti-HIP1 Antibody

Purpose: Anti-HIP1 Monoclonal Antibody

Characteristics: Anti-HIP1 Monoclonal Antibody (ABIN7605099). Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human HIP1 Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR) -mediated transcription.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ICC/IF 1:50-200
IP 1:30

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Alternative Name: HIP1

Background:

Synonyms: T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,CD8a,CD8A,MAL,

Tissue Specificity: Expressed at high levels in adult kidney, skeletal and placenta tissues and at very low levels in adult heart, lung and brain tissues. .

Molecular Weight: 116 kDa

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity