HNF1B antibody

Catalog No. ABIN7605145

The Rabbit Monoclonal anti-HNF1B antibody has been validated for WB. It is suitable to detect HNF1B in samples from Human, Rat and Mouse.

Quick Overview for HNF1B antibody (ABIN7605145)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HNF1B antibody is un-conjugated

Application: Western Blotting (WB)

Clone: HOH-8

Product Details anti-HNF1B Antibody

Purpose: Anti-HNF1 beta Rabbit Monoclonal Antibody

Characteristics: Anti-HNF1 beta Rabbit Monoclonal Antibody (ABIN7605145). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human HNF1 beta

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Alternative Name: HNF1B

Background:

Synonyms: Hepatocyte nuclear factor 1-beta,HNF-1-beta,HNF-1B,Homeoprotein LFB3,Transcription factor 2,TCF-2,Variant hepatic nuclear factor 1,vHNF1,HNF1B,TCF2,

Tissue Specificity: Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas. Normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth.

Molecular Weight: 42 kDa

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation