MSH2 antibody

Catalog No. ABIN7605602

This anti-MSH2 antibody is a Rabbit Monoclonal antibody detecting MSH2 in WB and FACS. Suitable for Human.

Quick Overview for MSH2 antibody (ABIN7605602)

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MSH2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: ACIH-13

Product Details anti-MSH2 Antibody

Purpose: Anti-MSH2 Monoclonal Antibody

Characteristics: Anti-MSH2 Monoclonal Antibody (ABIN7605602). Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human MSH2 MSH2 (MutS homologue 2) forms the hMutS- Alpha dimer with MSH6 and is an essential component of the mismatch repair process. hMutS- Alpha is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins and the Rad50-Mre11-NBS1 complex.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for MSH2

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Alternative Name: MSH2

Background:

Synonyms: Matrix metalloproteinase-9,MMP-9,3.4.24.35,92 kDa gelatinase,92 kDa type IV collagenase,Gelatinase B,GELB,67 kDa matrix metalloproteinase-9,82 kDa matrix metalloproteinase-9,MMP9,CLG4B,

Tissue Specificity: Produced by normal alveolar macrophages and granulocytes.

Molecular Weight: 25 kDa

UniProt: P43246

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response