SIN3A antibody

Catalog No. ABIN7605605

This anti-SIN3A antibody is a Rabbit Monoclonal antibody detecting SIN3A in WB, IF, IHC, ICC and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for SIN3A antibody (ABIN7605605)

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SIN3A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: ACEE-19

Product Details anti-SIN3A Antibody

Purpose: Anti-mSin3A Rabbit Monoclonal Antibody

Characteristics: Anti-mSin3A Rabbit Monoclonal Antibody (ABIN7605605). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human mSin3A Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Alternative Name: SIN3A

Background:

Synonyms: CD9 antigen,5H9 antigen,Cell growth-inhibiting gene 2 protein,Leukocyte antigen MIC3,Motility-related protein,MRP-1,Tetraspanin-29,Tspan-29,p24,CD9,CD9,MIC3, TSPAN29,GIG2,

Tissue Specificity: Detected in platelets (at protein level). Expressed by a variety of hematopoietic and epithelial cells. .

Molecular Weight: 17 kDa

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha