SIN3A antibody

Catalog No. ABIN7605605

The Rabbit Monoclonal anti-SIN3A antibody (Clone ACEE-19) (ABIN7605605) specifically detects SIN3A in WB, IHC, IF, FACS and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SIN3A antibody (ABIN7605605)

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SIN3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: ACEE-19

Product Details anti-SIN3A Antibody

Purpose: Anti-mSin3A Rabbit Monoclonal Antibody

Characteristics: Anti-mSin3A Rabbit Monoclonal Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human mSin3A Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000IHC 1:50-200ICC/IF 1:50-200FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Alternative Name: SIN3A

Background: SIN3 transcription regulator family member A

Molecular Weight: 17 kDa

Gene ID: 25942

UniProt: Q96ST3

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha