Merlin antibody

Catalog No. ABIN7605709

The Rabbit Monoclonal anti-Merlin antibody is suitable to detect Merlin in samples from Human, Mouse and Rat. It has been validated for WB and IP.

Quick Overview for Merlin antibody (ABIN7605709)

Target: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Merlin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: ACBB-14

Product Details anti-Merlin Antibody

Purpose: Anti-NF2 / Merlin Monoclonal Antibody

Characteristics: Anti-NF2 / Merlin Monoclonal Antibody (ABIN7605709). Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human NF2 / Merlin Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IP 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Merlin

Target: Merlin (NF2) (Neurofibromin 2 (NF2))

Alternative Name: NF2

Background:

Synonyms: C-X-C motif chemokine 10,10 kDa interferon gamma-induced protein,Gamma-IP10,IP-10,Small-inducible cytokine B10,CXCL10 (1-73),CXCL10,INP10, SCYB10,

Tissue Specificity: High expression is found in testis, spleen, colon and peripheral blood leukocytes. Low expression is found in other tissues.

Molecular Weight: 75 kDa

UniProt: P35240

Pathways: Cell-Cell Junction Organization