Melanoma gp100 antibody

Catalog No. ABIN7605996

This Rabbit Monoclonal antibody specifically detects Melanoma gp100 in IHC and WB. It exhibits reactivity toward Human.

Quick Overview for Melanoma gp100 antibody (ABIN7605996)

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Melanoma gp100 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: AHH-16

Product Details anti-Melanoma gp100 Antibody

Purpose: Anti-PMEL17 / GP100 Rabbit Monoclonal Antibody

Characteristics: Anti-PMEL17 / Rabbit Monoclonal Antibody (ABIN7605996). Tested in WB, IHC applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PMEL17 / GP100

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Alternative Name: PMEL

Background:

Synonyms: Melanocyte protein PMEL,ME20-M,ME20M,Melanocyte protein Pmel 17,Melanocytes lineage-specific antigen GP100,Melanoma-associated ME20 antigen,P1,P100,Premelanosome protein,Silver locus protein homolog,M-alpha,95 kDa melanocyte-specific secreted glycoprotein,P26,Secreted melanoma-associated ME20 antigen,ME20-S,ME20S,M-beta,PMEL,D12S53E, PMEL17, SILV,

Tissue Specificity: Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas. Normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth.

Molecular Weight: 100 kDa

UniProt: P40967