RENT1/UPF1 antibody
Quick Overview for RENT1/UPF1 antibody (ABIN7606163)
Target
See all RENT1/UPF1 (UPF1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-RENT1 / hUPF1 Rabbit Monoclonal Antibody
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Characteristics
- Anti-RENT1 / hUPF1 Rabbit Monoclonal Antibody (ABIN7606163). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human RENT1 / hUPF1
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Isotype
- IgG
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Application Notes
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WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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Alternative Name
- UPF1
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Background
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Synonyms: Protein lin-28 homolog B,Lin-28B,LIN28B,CSDD2,
Tissue Specificity: Expressed at high levels in the placenta and, at mucher lower, in testis and fetal liver (PubMed:16971064). Isoform 1 is only detected in placenta and in moderately and poorly differentiated hepatocellular carcinoma cells (at protein level). Isoform 2 is detected in fetal liver, non-tumor liver tissues, as well as well-differentiated tumor tissues (at protein level). Tends to be up-regulated in triple-negative (ER-,PR-,HER2-) breast tumors, as well as in liver, ovarian, and thyroid carcinomas (PubMed:22118463). .
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Molecular Weight
- 130 kDa
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UniProt
- Q92900
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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