CA9 antibody (Biotin)

Catalog No. ABIN7851489

The Biotin-conjugated Rabbit Monoclonal anti-CA9 antibody (Clone DM171) (ABIN7851489) specifically detects CA9 in ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for CA9 antibody (Biotin) (ABIN7851489)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CA9 antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: DM171

Product Details anti-CA9 Antibody (Biotin)

Purpose: Biotinylated Anti-CA9 antibody(DM171), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: CA9

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

UniProt: Q16790