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CSF1R antibody (Biotin)

The Rabbit Monoclonal anti-CSF1R antibody has been validated for ELISA and FACS. It is suitable to detect CSF1R in samples from Human.
Catalog No. ABIN7608170

Quick Overview for CSF1R antibody (Biotin) (ABIN7608170)

Target

See all CSF1R Antibodies
CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This CSF1R antibody is conjugated to Biotin

Application

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ELISA, Flow Cytometry (FACS)

Clone

DM106
  • Purpose

    Biotinylated Anti-CSF1R antibody(DM106), Rabbit mAb

    Purification

    Purified from cell culture supernatant by affinity chromatography

    Isotype

    IgG
  • Application Notes

    ELISA 1:5000-10000, Flow Cyt 1:100

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

    Alternative Name

    CSF1R

    Background

    The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1:PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

    UniProt

    P07333

    Pathways

    RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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