Recombinant FOLR2 antibody (Biotin)

Catalog No. ABIN7851657

The Biotin-conjugated Human Chimeric anti-FOLR2 antibody (Clone DMC390) (ABIN7851657) specifically detects FOLR2 in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant FOLR2 antibody (Biotin) (ABIN7851657)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This FOLR2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: DMC390

Product Details anti-FOLR2 Antibody (Biotin)

Purpose: Biotinylated Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: FOLR2

Background: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

UniProt: P14207

Pathways: Dicarboxylic Acid Transport