SNCA antibody (Biotin)

Catalog No. ABIN7695266

The Biotin-conjugated Rabbit Polyclonal anti-SNCA antibody (ABIN7695266) specifically detects SNCA in WB, IHC and ICC. The antibody is reactive with Human samples.

Quick Overview for SNCA antibody (Biotin) (ABIN7695266)

Target: SNCA (Synuclein, alpha (SNCA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNCA antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-SNCA Antibody (Biotin)

Purpose: Biotin-Linked Polyclonal Antibody to Synuclein Alpha (SNCa)

Specificity: The antibody is a rabbit polyclonal antibody raised against SNCa. It has been selected for its ability to recognize SNCa in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: PAB222Hu01Polyclonal Antibody to Synuclein Alpha (SNCa)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL
Immunocytochemistry in formalin fixed cells: 5-20 μg/mL
Immunohistochemistry in formalin fixed frozen section: 5-20 μg/mL
Immunohistochemistry in paraffin section: 5-20 μg/mL
Enzyme-linked Immunosorbent Assay: 0.05-2 μg/mL
Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: Synuclein Alpha

Background: SNC-A, aSYN, PD1, PARK1, PARK4, NACP, Non-A Beta Component Of Alzheimer's Disease Amyloid Precursor Protein, Non-A4 component of amyloid precursor

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity